WHAT IS ALLERGIC ASTHMA?

Asthma triggered by allergens?* It could be allergic asthma

That could mean that your asthma is not under control. The good news is that knowing your asthma is not controlled is the first step to finding relief!

Do you know if your allergic asthma is under control?

If you’re not treating allergic asthma for what it is, you may not be getting the relief you’re seeking. Allergic asthma that is uncontrolled with inhaled corticosteroids can take its toll—day and night. Ask yourself how you are really doing and if you've noticed any of these signs:

 

  • Are your symptoms getting worse and occurring more often than they used to?
  • Are you wheezing and coughing, or having chest tightness?
  • Do you wake up during the night because of your asthma?
  • Are you not getting enough relief from your inhaled corticosteroid treatment?
  • Do you reach for your rescue inhaler more than 2 days a week?
  • Have you been concerned that your asthma symptoms are not controlled with your current treatment plan?
8 times more

 

DID YOU KNOW?

For children with uncontrolled asthma, the odds are up to 8x greater that they will have a future attack.

*Triggers of allergic asthma

Pet dander is a year-round, airborne allergen that can cause allergic reactions

PET DANDER

Tiny flakes that shed from skin
and fur, similar to human dandruff
but harder to see.

Pet dander is a year-round, airborne allergen that can cause allergic reactions

PET DANDER

Tiny flakes that shed from
skin and fur, similar to human dandruff
but harder to see.

Dust mites are year-round, airborne allergens that can cause allergic reactions

DUST MITES

Critters that are too small
to be seen. They live
in household dust.

Dust mites are year-round, airborne allergens that can cause allergic reactions

DUST MITES

Critters that are too small
to be seen. They live
in household dust.

Cockroaches are year-round, airborne allergens that can cause allergic reactions

COCKROACHES

Cockroach remains
and debris are a major trigger
of allergic asthma.

Cockroaches are year-round, airborne allergens that can cause allergic reactions

COCKROACHES

Cockroach remains
and debris are a major
trigger of allergic asthma.

What happens during an allergic asthma attack

When you or someone you love breathes in a trigger (allergen), your body makes a substance called IgE (immunoglobulin E). High IgE levels cause a reaction in the lungs, which can lead to inflammation (swelling and narrow) in your airways. This inflammation can cause asthma symptoms that might lead to an asthma attack.
XOLAIR® (omalizumab) 75mg and 150mg syringe

Not actual size

Still coping with asthma symptoms?

XOLAIR may help


You’ve got a whole support network on your side

 Logo of the Xolair® (Omalizumab) Support for You program

From diagnosis to treatment, everyone’s experience is unique.

If you’ve been prescribed XOLAIR, the Support For You program is designed with YOU in mind.

Our free program provides relevant and timely support and resources.

IMPORTANT SAFETY INFORMATION & INDICATION

What is XOLAIR?

XOLAIR® (omalizumab) for subcutaneous use is an injectable prescription medicine used to treat moderate to severe persistent asthma in people 6 years of age and older whose asthma symptoms are not well controlled with asthma medicines called inhaled corticosteroids. A skin or blood test is performed to see if you have allergies to year-round allergens. It is not known if XOLAIR is safe and effective in people with asthma under 6 years of age.

XOLAIR is not used to treat sudden breathing problems.

What is the most important information I should know about XOLAIR?

Severe allergic reaction. A severe allergic reaction called anaphylaxis can happen when you receive XOLAIR. The reaction can occur after the first dose, or after many doses. It may also occur right after a XOLAIR injection or days later. Anaphylaxis is a life-threatening condition and can lead to death. Go to the nearest emergency room right away if you have any of these symptoms of an allergic reaction:

  • wheezing, shortness of breath, cough, chest tightness, or trouble breathing
  • low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of “impending doom”
  • flushing, itching, hives, or feeling warm
  • swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing

Your healthcare provider will monitor you closely for symptoms of an allergic reaction while you are receiving XOLAIR and for a period of time after treatment is initiated. Your healthcare provider should talk to you about getting medical treatment if you have symptoms of an allergic reaction.

Do not receive and use XOLAIR if you are allergic to omalizumab or any of the ingredients in XOLAIR.

Before receiving XOLAIR, tell your healthcare provider about all of your medical conditions, including if you:
  • have a latex allergy or any other allergies (seasonal allergies). The needle cap on the XOLAIR prefilled syringe contains a type of natural rubber latex.
  • have sudden breathing problems (bronchospasm)
  • have ever had a severe allergic reaction called anaphylaxis
  • have or have had a parasitic infection
  • have or have had cancer
  • are pregnant or plan to become pregnant. It is not known if XOLAIR may harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if XOLAIR passes into your breast milk. Talk with your healthcare provider about the best way to feed your baby while you receive and use XOLAIR.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

How should I receive and use XOLAIR?
  • When starting treatment, XOLAIR should be given by your healthcare provider in a healthcare setting.
  • If your healthcare provider decides that you or a caregiver may be able to give your own XOLAIR prefilled syringe or autoinjector injections, you should receive training on the right way to prepare and inject XOLAIR.
  • Do not try to inject XOLAIR until you have been shown the right way to give XOLAIR prefilled syringe or autoinjector injections by a healthcare provider. Use XOLAIR exactly as prescribed by your healthcare provider.
  • The XOLAIR autoinjector (all doses) is intended for use only in adults and adolescents aged 12 years and older. For children 12 years of age and older, XOLAIR prefilled syringe or autoinjector may be self-injected under adult supervision. For children 1 to 11 years of age, XOLAIR prefilled syringe should be injected by a caregiver.
  • See the detailed Instructions for Use that comes with XOLAIR for information on the right way to prepare and inject XOLAIR.
  • XOLAIR is given in 1 or more injections under the skin (subcutaneous), 1 time every 2 or 4 weeks.
  • In people with asthma, a blood test for a substance called IgE must be performed before starting XOLAIR to determine the appropriate dose and dosing frequency.
  • Do not decrease or stop taking any of your other asthma medicine unless your healthcare providers tell you to.
  • You may not see improvement in your symptoms right away after XOLAIR treatment. If your symptoms do not improve or get worse, call your healthcare provider.
  • If you inject more XOLAIR than prescribed, call your healthcare provider right away.
What are the possible side effects of XOLAIR?
XOLAIR may cause serious side effects, including:
  • Cancer. Cases of cancer were observed in some people who received XOLAIR.
  • Inflammation of your blood vessels. Rarely, this can happen in people with asthma who receive XOLAIR. This usually, but not always, happens in people who also take a steroid medicine by mouth that is being stopped or the dose is being lowered. It is not known whether this is caused by XOLAIR. Tell your healthcare provider right away if you have rash; chest pain; shortness of breath; or a feeling of pins and needles or numbness of your arms or legs.
  • Fever, muscle aches, and rash. Some people get these symptoms 1 to 5 days after receiving a XOLAIR injection. If you have any of these symptoms, tell your healthcare provider.
  • Parasitic infection. Some people who are at a high risk for parasite (worm) infections, get a parasite infection after receiving XOLAIR. Your healthcare provider can test your stool to check if you have a parasite infection.
  • Heart and circulation problems. Some people who receive XOLAIR have had chest pain, heart attack, blood clots in the lungs or legs, or temporary symptoms of weakness on one side of the body, slurred speech, or altered vision. It is not known whether these are caused by XOLAIR
The most common side effects of XOLAIR:
  • In adults and children 12 years of age and older with asthma: joint pain especially in your arms and legs, dizziness, feeling tired, itching, skin rash, bone fractures, and pain or discomfort of your ears.
  • In children 6 to less than 12 years of age with asthma: swelling of the inside of your nose, throat, or sinuses, headache, fever, throat infection, ear infection, abdominal pain, stomach infection, and nose bleeds.

These are not all the possible side effects of XOLAIR. Call your doctor for medical advice about side effects.

You may report side effects to the FDA at (800) FDA-1088 or www.fda.gov/medwatch. You may also report side effects to Genentech at (888) 835-2555 or Novartis Pharmaceuticals Corporation at (888) 669-6682.

Please see full Prescribing Information, including Medication Guide, for additional Important Safety Information and Instructions for Use.